D-GLUCARAT 200mg

CALCIUM D-GLUCARAT

200 mg/60 cps.

Calitate ultrapura

Made by Organika

ISO 9001/ GMP

ANTI-CARCINOGEN, ANTI-TUMORAL, DETOXIFIANT

ELIMINA EXCESUL DE ESTROGEN DIN FICAT

Calciul D-Glucarat este sarea calcica a Acidului D-Glucaric, o substanta produsa natural de catre mamifere inclusiv omul dar in cantitati extreme de mici. Este insa substanta care ajuta organismul sa elimine toxinele in special cele carcinogene. Suplimentarea pe cale orala cu Calciu D-Glucarat inhiba beta-glucuronidaza, o enzima produsa de microflora din colon si care este implictata in Faza II de detoxificare a ficatului. Prezenta in exces a beta-glucuronidazei este legata direct de riscurile marite pentru aparitia cancerelor cum ar fi la colon, san, prostata, plaman, etc. O alta fateta benefica a suplimentarii cu Calciu D-Glucarat este reglarea metabolismului estrogenului PRIN ELIMINAREA EXCESULUI DE ESTROGEN DIN FICAT (in special la femei) si reducerea nivelului de lipide.

Pe scurt, CalciuD-Glucarat micsoreaza nivelul de glucuronidaza, si prin aceasta permite organismului sa elimine carcinogenii (substante chimice care cauzeaza cancer). Eliminarea carcinogenilor se face in special prin fecale, prin urmare este nevoie de un colon curat (nota: pentru curatirea colonului avem in farmacie produsul CURATITOR COLON)

In 1990, Walaszek (descoperitorul efectelor D-Glucaratului) s-a mutat la Centrul de Carcinogeneza MD Andersondin Houston, texas unde si-a continuat cercetarile. In mai multe articole publicate ulterior el arata ca Calciul D-Glucarat reduce “proliferarea’ tumorilor, cu alte cuvinte prezenta acestui agent le incetineste cresterea.

In 1991, 1992, 1993 si 1994 echipa Dr. Walaszek a efectuat mai multe teste atat pe animale cat si pe oameni demonstarnd ca doze mici de Calciu D-Glucarat administrate oral sunt convertite imediat in D-Glucaro-lactona care conduce la o activitate anti-tumorala marita a rentinoidelor. Pur si simplu, prin administrarea D-Glucaratului a fost imposibil sa se induca cancere prin metodele obisnuite de stimulare a cresterii tumorale.

Tehnologia de extragere si purificare a Calciului D-Glucarat este patentata in Statele Unite.

Calciu D-Glucarat este parte integranta a protocolului nostru DETOXIN

COMPOZITIE:

CalciuD-Glucarat…………………200 mg

ADMINISTRARE:

1-2 capsule pe zi cu 30 minute inainte de mese.

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BIBLIOGRAFIE:

1. Walaszek, Z., Hanausek, M., Szemraj, J., and Adams, A.K.1998,

D-Glucarate acid as a prospective tumor marker. Meth. Mol.Med., 14,

487-495.
2. Walaszek, Z., Szemraj, J., Adams, A.K., and Hanausek, M. 1992,

Reduced levels of D-Glucaric acid in mammary tumor-bearing hosts and

the effect of its supplementation during estrogen replacement and tamoxifin

therapy. Proc. Am. Assoc. Cancer Res. 37: 183.
3. Heerdt, A.S., Young, C.W.., and Borgen, P.I., 1995, Calcium Glucarate

as a chemopreventative agent in breast cancer., Isr. J. Med. Sci. 31:

101-105.
4. Walaszek, Z.Chemopreventativeproperties of D-Glucaric acid

derivatives. Cancer Bull 1993; 45: 453-457.
5. Walaszek, Z., Szemraj, J., Adams, A.K., Kordari, P., and Hanausek, M.

1992, Reduced levels of D-Glucaric acid in mammary tumor-bearing Host.

Breast Cancer Res.Treat., 375: 108.
6. Walaszek, Z., Hanausek, M., Adams, A.K.and Sherman, U. 1991,

Cholesterol lowering effects of dietary D-Glucarate. FasebJ., 5: A930.
7. Walaszek, Z., Hanausek, M., Sherman, U. and Adams, A.K.1990,

Antiproliferative effect of dietary glucarate on the SpragueDawleyin rat

mammary gland. Cancer Lett. 49: 51-57.
8. Walaszek, Z., Adams, A.K., Sherman, U., Viaje, A., Rotstein, J.B.,

Hanausek, M. and Slaga, T.J. 1990, Antiproliferate effects of Calcium

D-Glucarate (CG) and D-glucaro-1,4-lactone (GL) on the rat mammary

gland, colon and mouse skin. Proc. Am. Assoc. Cancer Res., 31: 124. p>
9. Walaszek, Z. 1990, Potential use of D-Glucarate acid derivatives in

cancer prevention. Cancer Lett. 54: 1-8.
10. DiGiovanni, J., 1990, Inhibition of chemical carcinogenesis. In:

Chemical Carcinogenesis and Mutagenesis II, Cooper, C.S.and Grover,
P.L.(eds.), Springer Verlag, Berlin, pp. 159-224.
11. Walaszek, Z., Adams, A.K., and Flores, F., 1989, Inhibition of

7,12-dimethylbenz(a)-anthracene(DMBA)-induced rat mammary

carcinogenesis by glucarate. Proc. Am. Assoc. Cancer Res., 30: 170.
12. Abbou-Issa, H., Koolemans-Beynen, A., Minton, J.P.and Webb, T.E.,

1989, Synergistic interaction between 13-cis-retinoic acid and glucarate:

activity against rat mammary tumor induction and MCF-7 cells. Biochem.

Biophys. Res.Commun.,163: 1364-1369.
13. Dwivedi, C., Oredipe, O.A., Barth, R.F., Downie, A.A.and Webb, T.E.,

1989, Effects of the experimental chemopreventative agent, glucarate on

intestinal carcinogenesis in rats. Carcinogenesis, 10: 1539-1541.
14. Oredipe, O.A., Barth, R.F., Dwivedi, C. and Webb, T.E., 1989,

Chemopreventative activity of dietary glucarate on azoxymethane-induced

altered hepatic loci in rats. Res.Commun. Chem.Pathol. Pharmacol., 65:

345-359.
15. Dwivedi. C., Downie, A.A.and Webb, T.E., 1989, Modulation of

chemically initiated and promoted skin tumorigenesis in CD-1 mice by

dietary glucarate. J. Environ. Path. Toxicol. Oncol., 9: 253-259.
16. Walaszek, Z., Hanausek, M., Sherman, U., Del Rio, M. and Adams,
A.K., 1989, Effects of (+) glucaric acid derivatives and tamoxifen on human

breast cancer cells (MCF-7). Breast Cancer Res.Treat., 14: 175.
17. Walaszek, Z., Flores, F. and Adams, A.K., 1988, Effect of dietary

glucarate on estrogen receptors and growth of 7,12-dimethylbenz[a]

anthracene-induced rat mammary carcinomas. Breast Cancer Res.Treat.,

12: 128.
18. Walaszek, Z., Hanausek-Walaszek, M. and Webb, T.E., 1988,

Repression by sustained release or glucuronidase inhibitors of chemical

carcinogen-mediated induction of a marker oncofetal protein in rodents. J.
Toxicol. Environ. Health, 23: 15-27.
19. Abbou-Issa, H.M., Duruibe, V.A., Minton, J.P., Larroya, S., Dwivedi,

C., and Webb, T.E., 1988, Putative metabolites derived from dietary

combinations of calcium glucarate and N-(4hydroxypheny)retinamide act

synergistically to inhibit the induction of rat mammary rumors by

7,12-dimethylbenz[a]-anthracene. Proc. Natl. Acad. Sci. USA. 85:

4181-4184.
20. Oredipe, O.A., Barth, R.F., Hanausek-Walaszek, M., Sautins, I.,

Walaszek, Z. and Webb, T.E.1987, Effects of an inhibitor of

B-glucuronidase on hepatocarcinogenesis. Proc. Am. Assoc. Cancer Res.,

28: 156.
21. Oredipe, O.A., Barth, R.F., Hanausek-Walaszek, M., Sautins, I.

Walaszek, Z. and Webb, T.E.1987, Effects of calcium glucarate on the

promotion of diethylnitrosamine-initiated altered hepatic loci in rats.

Cancer. Lett., 38, 95-99.
22. Walaszek, Z., Hanausek-Walaszek, M., Minton, J.P. and Webb, T.E.

1986, Dietary glucarate as antipromoter of

7,12-dimethylbenz[a]-anthra-cene-induced mammary tumorigenesis.

Carcinogenesis, 7:1463-1466.
23. Minton, J.P., Walaszek, Z., Hanausek-Walaszek, M., and Webb, T.E.

1986, B-Glucuronidase levels in patients with fibrocystic breast disease.

Breast Cancer Res.Treat., 8: 217-222.
24. Walaszek, Z., Hanausek-Walaszek, M., Webb, T.E., 1986, Dietary

glucarate-mediated reduction of sensitivity of murine strains to chemical to

chemical carcinogenesis. Cancer Lett., 33: 25-32.